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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">atu</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник Алматинского технологического университета</journal-title><trans-title-group xml:lang="en"><trans-title>The Journal of Almaty Technological University</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-568X</issn><issn pub-type="epub">2710-0839</issn><publisher><publisher-name>АО "АТУ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.48184/2304-568X-2021-3-25-33</article-id><article-id custom-type="elpub" pub-id-type="custom">atu-439</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТЕХНОЛОГИЯ ПИЩЕВОЙ И ПЕРЕРАБАТЫВАЮЩЕЙ ПРОМЫШЛЕННОСТИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOOD AND PROCESSING INDUSTRY TECHNOLOGY</subject></subj-group></article-categories><title-group><article-title>Исследование витаминного состава лекарственных трав при разработке иммуностимулирующих кондитерских изделий</article-title><trans-title-group xml:lang="en"><trans-title>Research of the vitamin composition of medicinal herbs in the development of immunostimulating confectionery products</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0395-3379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пронина</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Pronina</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>050012, г. Алматы, ул. Толе би, 100</p></bio><bio xml:lang="en"><p>050012, city of Almaty, Tole bi str., 100</p></bio><email xlink:type="simple">medvezhonok_87@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7258-746X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Набиева</surname><given-names>Ж. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nabiyeva</surname><given-names>Zh. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>050012, г. Алматы, ул. Толе би, 100</p></bio><bio xml:lang="en"><p>050012, city of Almaty, Tole bi str., 100</p></bio><email xlink:type="simple">atu_nabiyeva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7854-1523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Базылханова</surname><given-names>Э. Ч.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazylkhanova</surname><given-names>E. Ch.</given-names></name></name-alternatives><bio xml:lang="ru"><p>050012, г. Алматы, ул. Толе би, 100</p></bio><bio xml:lang="en"><p>050012, city of Almaty, Tole bi str., 100</p></bio><email xlink:type="simple">66bel@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2149-9811</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белозерцева</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Belozertseva</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>050012, г. Алматы, ул. Толе би, 100</p></bio><bio xml:lang="en"><p>050012, city of Almaty, Tole bi str., 100</p></bio><email xlink:type="simple">nik_belozerceva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самадун</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Samadun</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>050012, г. Алматы, ул. Толе би, 100</p></bio><bio xml:lang="en"><p>050012, city of Almaty, Tole bi str., 100</p></bio><email xlink:type="simple">abdu.93_93@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">АО «Алматинский технологический университет»<country>Казахстан</country></aff><aff xml:lang="en">«Almaty Technological University », JSC<country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>3</issue><fpage>25</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пронина Ю.Г., Набиева Ж.С., Базылханова Э.Ч., Белозерцева О.Д., Самадун А.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Пронина Ю.Г., Набиева Ж.С., Базылханова Э.Ч., Белозерцева О.Д., Самадун А.И.</copyright-holder><copyright-holder xml:lang="en">Pronina Y.G., Nabiyeva Z.S., Bazylkhanova E.C., Belozertseva O.D., Samadun A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://atu.ejournal.kz/jour/article/view/439">https://atu.ejournal.kz/jour/article/view/439</self-uri><abstract><p>В данной статье отражены результаты исследования содержания витаминов, полифенолов, антиоксидантов в лекарственном сырье местного происхождения (корень солодки, зверобой, листья облепихи, корень имбиря, калина, цикорий, мать-и-мачеха, корневища алтея, корень девясила, тысячелистник, плоды рябины, плоды шиповника, семена льна) в целях изучения их полезных свойств в качестве компонента для мармеладных изделий, обладающих иммуностимулирующим действием. Согласно проведенным лабораторным исследованиям, наибольшее количество полифенолов содер-жится в листьях облепихи и зверобое (60,02% и 12,82% соответственно), антиоксидантов (3,61 мг/100 г и 2,49 мг/100г) и большая часть витаминов группы В (В₂ в листьях облепихи 0,777 мг/100 г, а в зверобое 0,088 мг/100 г, В₅ – 1,506 мг/100г и 0,061 мг/100г соответственно, В₆ – 0,680 мг/100 г в листьях облепихи и 0,427 мг/100 г в зверобое). Высокое содержание витамина С выявлено в шиповнике (4,355 мг/100г) и зверобое (4,314 мг/100г). В листьях облепихи содержание аскорбиновой кислоты составляет 1,409 мг/100 г, что на 67% меньше по сравнению со зверобоем. В связи с этим следует, что наиболее перспективным сырьем для придания иммуностимулирующего действия мармеладным кондитерским изделиям являются листья облепихи и зверобой.</p></abstract><trans-abstract xml:lang="en"><p>This article reflects the results of a study of the content of vitamins, polyphenols, antioxidants in medicinal raw materials of local origin (licorice root, St. rose hips, flax seeds) in order to study their beneficial properties as a component for marmalade products that have an immunostimulating effect. According to laboratory studies, the largest amount of polyphenols is found in the leaves of sea buckthorn and St. John's wort (60.02% and 12.82%, respectively), antioxidants (3.61 mg / 100 g and 2.49 mg / 100 g) and most of the B vitamins (В₂ in sea buckthorn leaves 0.777 mg / 100 g, and in St. John's wort 0.088 mg / 100 g, В₅ - 1.506 mg / 100 g and 0.061 mg / 100 g, respectively, В₆ - 0.680 mg / 100 g in sea buckthorn leaves and 0.427 mg / 100 g in St. John's wort). A high content of vitamin C was found in rose hips (4.355 mg / 100g) and St. John's wort (4.314 mg / 100g). In the leaves of sea buckthorn, the content of ascorbic acid is 1.409 mg / 100 g, which is 67% less compared to St. John's wort. In this regard, it follows that the most promising raw materials for imparting an immunostimulating effect to marmalade confectionery products are sea buckthorn leaves and St. John's wort.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>витамины</kwd><kwd>полифенолы</kwd><kwd>антиоксиданты</kwd><kwd>лекарственные травы</kwd><kwd>кондитерские изделия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vitamins</kwd><kwd>polyphenols</kwd><kwd>antioxidants</kwd><kwd>medicinal herbs</kwd><kwd>confectionery</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследования проводятся в Алматинском технологическом университете, г. Алматы, Республики Казахстан в рамках проекта №AP09058293 «Разработка технологии производства диетических иммуностимулирующих кондитерских изделий на основе переработки местного растительного сырья», финансируемого Министерством образования и науки Республики Казахстан.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Докучаева Е.А., Сяхович В.Э., Богданова Н.В. Общая биохимия: Витамины: практикум. – Минск: ИВЦ Минфина, 2017. – 52 c.</mixed-citation><mixed-citation xml:lang="en">Dokuchaeva E.A., Sjahovich V.Je., Bogdanova N.V. Obshhaja biohimija: Vitaminy: praktikum. – Minsk: IVC Minfina, 2017. – 52 c. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ламажапова Г.П. Физиология питания. Учебное пособие - М.: Мир науки, 2016. – 146 с.</mixed-citation><mixed-citation xml:lang="en">Lamazhapova G.P. Fiziologija pitanija. Uchebnoe posobie - M.: Mir nauki, 2016. – 146 s. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кукенов М.К.. Аверина В.Ю. и др. Лекарственные растения Казахстана и их исполь-зование. – Казахстан: Алматы: Ғылым, 1996. –344 с.</mixed-citation><mixed-citation xml:lang="en">Kukenov M.K.. Averina V.Ju. i dr. Lekarstvennye rastenija Kazahstana i ih ispol'-zovanie. – Kazahstan: Almaty: Ғylym, 1996. –344 s. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Abolfathi M.E., Tabeidian S.A., Shahraki A.D.F., Tabatabaei S.N., Habibian M. Ethanol extract of elecampane (Inulahelenium L.) rhizome attenuates experimental cold-induced ascites (pulmonary hypertension syndrome) in broiler chickens //Animal Feed Science and Technology, 2021. – Vol. 272. – P. 114755. https://doi.org/10.1016/j.anifeedsci.2020.114755.</mixed-citation><mixed-citation xml:lang="en">Abolfathi M.E., Tabeidian S.A., Shahraki A.D.F., Tabatabaei S.N., Habibian M. Ethanol extract of elecampane (Inulahelenium L.) rhizome attenuates experimental cold-induced ascites (pulmonary hypertension syndrome) in broiler chickens //Animal Feed Science and Technology, 2021. – Vol. 272. – P. 114755. https://doi.org/10.1016/j.anifeedsci.2020.114755.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dyakova N.A., Gaponov S.P., Slivkin A.I., Belenova A.S., Karlov P.M., Lavrov S.V. Elaboration of an express technique for inulin extraction from the roots of elecampane (Inulahelenium L.) IOP Conference Series: Earth and Environmental Science. – IOP Publishing, 2021. – Vol. 640. – №052021 P. 1-5. https://doi.org/10.1088/1755-1315/640/5/052021.</mixed-citation><mixed-citation xml:lang="en">Dyakova N.A., Gaponov S.P., Slivkin A.I., Belenova A.S., Karlov P.M., Lavrov S.V. Elaboration of an express technique for inulin extraction from the roots of elecampane (Inulahelenium L.) //IOP Conference Series: Earth and Environmental Science. – IOP Publishing, 2021. – Vol. 640. – №052021 P. 1-5. https://doi.org/10.1088/1755-1315/640/5/052021.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lubsandorzhieva P.B., Rendyuk T.D., Dashinamzhilov Zh.B., Dargaeva T.D., Ferubko E.V. Pharmacognostic Study of Collection and Study of its Hepatoprotective Activity// Pharmacognosy Journal, 2021. – Vol.13,3. - P.713-721. https://doi.org/ 10.5530/pj.2021.13.91.</mixed-citation><mixed-citation xml:lang="en">Lubsandorzhieva P.B., Rendyuk T.D., Dashinamzhilov Zh.B., Dargaeva T.D., Ferubko E.V. Pharmacognostic Study of Collection and Study of its Hepatoprotective Activity// Pharmacognosy Journal, 2021. – Vol.13,3. - P.713-721. https://doi.org/ 10.5530/pj.2021.13.91.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson-Dekkers I., Nouwens-Roest M., Peters B., Vaughan E. ‘Chapter 17 - Inulin’. Handbook of Hydrocolloids (Third Edition). Ed. by G.O. Phillips and P.A. Williams. Third Edition. Woodhead Publishing, 2021. – 948 p. DOI: https://doi.org/10.1016/B978-0-12-820104-6.00015- 2.</mixed-citation><mixed-citation xml:lang="en">Anderson-Dekkers I., Nouwens-Roest M., Peters B., Vaughan E. ‘Chapter 17 - Inulin’. Handbook of Hydrocolloids (Third Edition). Ed. by G.O. Phillips and P.A. Williams. Third Edition. Woodhead Publishing, 2021. – 948 p. DOI: https://doi.org/10.1016/B978-0-12-820104-6.00015- 2.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Watson A.W., Houghton D., Avery P.J., Stewart C., Vaughan E.E., Meyer P.D., de BosKuil M.J.J., Weijs P.J.M., Brandt K. Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota //Food hydrocolloids, 2019. – Vol. 96. – P. 688-698. https://doi.org/10.1016/j.foodhyd.2019.06.006.</mixed-citation><mixed-citation xml:lang="en">Watson A.W., Houghton D., Avery P.J., Stewart C., Vaughan E.E., Meyer P.D., de BosKuil M.J.J., Weijs P.J.M., Brandt K. Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota //Food hydrocolloids, 2019. – Vol. 96. – P. 688-698. https://doi.org/10.1016/j.foodhyd.2019.06.006.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wu R., Yang J., Wang L., Xiujuan G. Physiological response of flax seedlings with different drought-resistances to drought stress// Acta Agric Boreali-Sinica, 2019.- Vol.34. - P. 145-153.</mixed-citation><mixed-citation xml:lang="en">Wu R., Yang J., Wang L., Xiujuan G. Physiological response of flax seedlings with different drought-resistances to drought stress// Acta Agric Boreali-Sinica, 2019.- Vol.34. - P. 145-153.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Conforti F.D., Davis S.F. The effect of soya flour and flaxseed as a partial replacement for bread flour in yeast bread// International Journal of Food Science and Technology, 2006. – Vol.41 (SUPPL. 2), P. 95-101. doi: https://doi.org/10.1111/j.1365-2621.2006.01410.x.</mixed-citation><mixed-citation xml:lang="en">Conforti F.D., Davis S.F. The effect of soya flour and flaxseed as a partial replacement for bread flour in yeast bread// International Journal of Food Science and Technology, 2006. – Vol.41 (SUPPL. 2), P. 95-101. doi: https://doi.org/10.1111/j.1365-2621.2006.01410.x.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rajiv J., Indrani D., Prabhasankar P., Venkateswara Rao G. Rheology, fatty acid profile and storage characteristics of cookies as influenced by flax seed (Linumusitatissimum)// J Food Sci Technol, 2012. – Vol.49, P.587–593. https://doi.org/10.1007/s13197-011-0307-2.</mixed-citation><mixed-citation xml:lang="en">Rajiv J., Indrani D., Prabhasankar P., Venkateswara Rao G. Rheology, fatty acid profile and storage characteristics of cookies as influenced by flax seed (Linumusitatissimum)// J Food Sci Technol, 2012. – Vol.49, P.587–593. https://doi.org/10.1007/s13197-011-0307-2.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bokov D.O., Sharipova R.I., Potanina O.G., Nikulin A.V., Nasser R.A., Samylina I.A., Chevidaev V.V., Kakhramanova S.D., Sokhin D.M., Klyukina E.S., Rendyuk T.D., Janulis V., Krasnyuk I.I., Bessonov V.V. Polysaccharides of crude herbal drugs as a group of biologically active compounds in the field of modern pharmacognosy: physicochemical properties, classification, pharmacopoeial analysis // Systematic Review Pharmacy, 2020. – Vol. 11. – №6. – P. 206-212. https://doi.org/10.31838/srp.2020.6.32.</mixed-citation><mixed-citation xml:lang="en">Bokov D.O., Sharipova R.I., Potanina O.G., Nikulin A.V., Nasser R.A., Samylina I.A., Chevidaev V.V., Kakhramanova S.D., Sokhin D.M., Klyukina E.S., Rendyuk T.D., Janulis V., Krasnyuk I.I., Bessonov V.V. Polysaccharides of crude herbal drugs as a group of biologically active compounds in the field of modern pharmacognosy: physicochemical properties, classification, pharmacopoeial analysis // Systematic Review Pharmacy, 2020. – Vol. 11. – №6. – P. 206-212. https://doi.org/10.31838/srp.2020.6.32.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Van der Gaag E.J., Hummel T.Z. Food or medication? The therapeutic effects of food on the duration and incidence of upper respiratory tract infections: a Review of the literature //Critical Reviews in Food Science and Nutrition. – 2020. – P. 1-14.</mixed-citation><mixed-citation xml:lang="en">Van der Gaag E.J., Hummel T.Z. Food or medication? The therapeutic effects of food on the duration and incidence of upper respiratory tract infections: a Review of the literature //Critical Reviews in Food Science and Nutrition. – 2020. – P. 1-14.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bobinaitė R., Kraujalis P., Tamkutė L., Urbonavičienė D., Viškelis P., Venskutonis P.R. Recovery of bioactive substances from rowanberry pomace by consecutive extraction with supercritical carbon dioxide and pressurized solvents //Journal of Industrial and Engineering Chemistry, 2020. – Vol. 85. – P. 152-160.</mixed-citation><mixed-citation xml:lang="en">Bobinaitė R., Kraujalis P., Tamkutė L., Urbonavičienė D., Viškelis P., Venskutonis P.R. Recovery of bioactive substances from rowanberry pomace by consecutive extraction with supercritical carbon dioxide and pressurized solvents //Journal of Industrial and Engineering Chemistry, 2020. – Vol. 85. – P. 152-160.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kajszczak D., Zakłos-Szyda M., Podsędek A. Viburnum opulus L.— А review of phytochemistry and biological effects //Nutrients, 2020. – Vol. 12. – №11.p 3398. https://doi.org/10.3390/nu12113398.</mixed-citation><mixed-citation xml:lang="en">Kajszczak D., Zakłos-Szyda M., Podsędek A. Viburnum opulus L.— А review of phytochemistry and biological effects //Nutrients, 2020. – Vol. 12. – №11, 3398. https://doi.org/10.3390/nu12113398.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Yıldız R., Ekici H., Yarsan E. Antioxidant effects of viburnum opulus on streptozotocin-induced experimental diabetic rats //Journal of Applied Biological Sciences, 2020. – Vol. 14. – №2. – P. 124-135.</mixed-citation><mixed-citation xml:lang="en">Yıldız R., Ekici H., Yarsan E. Antioxidant effects of viburnum opulus on streptozotocin-induced experimental diabetic rats //Journal of Applied Biological Sciences, 2020. – Vol. 14. – №2. – P. 124-135.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Pramono S. Utilisation and functional components evaluation of ginger //Ginger Cultivation and Its Antimicrobial and Pharmacological Potentials, 2020. – P. 1-14.</mixed-citation><mixed-citation xml:lang="en">Pramono S. Utilisation and functional components evaluation of ginger //Ginger Cultivation and Its Antimicrobial and Pharmacological Potentials, 2020. – P. 1-14.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Amreen K., Shukla V., Shukla S., Rajagopal D., Kumar A.S. Redox behaviour and surface-confinement of electro active species of ginger extract on graphitized mesoporous carbon surface and its copper complex for H2O2 sensing //Nano-Structures &amp; Nano-Objects, 2017. – Vol. 11. – P. 56-64. DOI:10.1016/j.nanoso.2017.06.004.</mixed-citation><mixed-citation xml:lang="en">Amreen K., Shukla V., Shukla S., Rajagopal D., Kumar A.S. Redox behaviour and surface-confinement of electro active species of ginger extract on graphitized mesoporous carbon surface and its copper complex for H2O2 sensing //Nano-Structures &amp; Nano-Objects, 2017. – Vol. 11. – P. 56-64. DOI:10.1016/j.nanoso.2017.06.004.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Myint M.M., Khine M.M. Determination of Bioactivities and Identification of Isolated Compounds from the Rhizome of Zingiber officinale Roscoe (Ginger)// Dagon University Research Journal, 2017. - Vol. 10 – P.85-93.</mixed-citation><mixed-citation xml:lang="en">Myint M.M., Khine M.M. Determination of Bioactivities and Identification of Isolated Compounds from the Rhizome of Zingiber officinale Roscoe (Ginger)// Dagon University Research Journal, 2017. - Vol. 10 – P.85-93.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">ГОСТ 31483-2012. Премиксы. Опре-деление содержания витаминов: B (тиаминхло-рида), B (рибофлавина), B (пантотеновой кислоты), B (никотиновой кислоты и никотинамида), B (пиридоксина), B (фолиевой кислоты), C (аскорбиновой кислоты) методом капиллярного электрофореза. - Введ. 2013-07-01.- М.: Стандартинформ, 2012.– 17 с.</mixed-citation><mixed-citation xml:lang="en">GOST 31483-2012. Premiksy. Opre-delenie soderzhanija vitaminov: B (tiaminhlo-rida), B (riboflavina), B (pantotenovoj kisloty), B (nikotinovoj kisloty i nikotinamida), B (piridoksina), B (folievoj kisloty), C (askorbinovoj kisloty) metodom kapilljarnogo jelektroforeza. - Vved. 2013-07-01.- M.: Standartinform, 2012.– 17 s. (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Kukharenko A., Brito A., Yashin Y.I, Yashin, A.Y., Kuznetsov R.M., Markin P.A., Bochkareva, N.L., Pavlovskiy I.A., Appolonova S.A. Total antioxidant capacity of edible plants commonly found in East Asia and the Middle East determined by an amperometric method// Food Measure, 2020. – Vol.14. – P. 809–817. DOI: https://doi.org/10.1007/s11694-019-00329-8.</mixed-citation><mixed-citation xml:lang="en">Kukharenko A., Brito A., Yashin Y.I, Yashin, A.Y., Kuznetsov R.M., Markin P.A., Bochkareva, N.L., Pavlovskiy I.A., Appolonova S.A. Total antioxidant capacity of edible plants commonly found in East Asia and the Middle East determined by an amperometric method// Food Measure, 2020. – Vol.14. – P. 809–817. DOI: https://doi.org/10.1007/s11694-019-00329-8.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Murzahmetova M.K., Tayeva A.M., Baimaganbetova G.B., Nabiyeva Z.S., Kizatova M.Z., Kulazhanov K.S., Vitavskaya A.V. Antioxidant activity of breads // Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015. - Vol. 6. - I. 3. - P. 1020-1025.</mixed-citation><mixed-citation xml:lang="en">Murzahmetova M.K., Tayeva A.M., Baimaganbetova G.B., Nabiyeva Z.S., Kizatova M.Z., Kulazhanov K.S., Vitavskaya A.V. Antioxidant activity of breads // Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2015. - Vol. 6. - I. 3. - P. 1020-1025.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Hernandez-Vazquez A.D.J., Garcia-Sanchez J.A., Moreno-Arriola E., Salvador-Adriano A., Ortega-Cuellar D., Velazquez-Arellano A. Thiamine Deprivation Produces a Liver ATP Deficit and Metabolic and Genomic Effects in Mice: Findings Are Parallel to Those of Biotin Deficiency and Have Implications for Energy Disorders // Journal of Nutrigenetics and Nutrigenomics, 2016. – Vol. 9 (5-6). - P. 287-299. - ISSN 1661-6758. DOI:10.1159/000456663.</mixed-citation><mixed-citation xml:lang="en">Hernandez-Vazquez A.D.J., Garcia-Sanchez J.A., Moreno-Arriola E., Salvador-Adriano A., Ortega-Cuellar D., Velazquez-Arellano A. Thiamine Deprivation Produces a Liver ATP Deficit and Metabolic and Genomic Effects in Mice: Findings Are Parallel to Those of Biotin Deficiency and Have Implications for Energy Disorders // Journal of Nutrigenetics and Nutrigenomics, 2016. – Vol. 9 (5-6). - P. 287-299. - ISSN 1661-6758. DOI:10.1159/000456663.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Scimone C., Alibrandi S., Donato L., Giofre S.V., Rao G., Sidoti A., D'Angelo R. Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin // Journal of clinical pharmacy and therapeutics, 2020. – Vol. 46 (2). - P. 304-309. DOI: 10.1111/jcpt.13315.</mixed-citation><mixed-citation xml:lang="en">Scimone C., Alibrandi S., Donato L., Giofre S.V., Rao G., Sidoti A., D'Angelo R. Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin // Journal of clinical pharmacy and therapeutics, 2020. – Vol. 46 (2). - P. 304-309. DOI: 10.1111/jcpt.13315.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Nizhenkovska I., Narokha V., Kuznetsova O. Effects of nicotinic acid on protein oxidative modifications in experimental chronic heart failure //Farmacia, 2018. - Vol. 66, 6. - P. 959-962. DOI: HTTP://DOI.ORG/10.31925/FARMACIA.2018.6.5.</mixed-citation><mixed-citation xml:lang="en">Nizhenkovska I., Narokha V., Kuznetsova O. Effects of nicotinic acid on protein oxidative modifications in experimental chronic heart failure // Farmacia, 2018. - Vol. 66, 6. - P. 959-962. DOI: HTTP://DOI.ORG/10.31925/FARMACIA.2018.6.5.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ceri N.G., Gulle K., Arasli M., Akpolat M., Demirci B. Protective Effect of Vitamin B5 (Dexpanthenol) on Nephropathy in Streptozotocin Diabetic Rats// Meandros medical and dental journal, 2021. – Vol. 22. - P. 53-56. DOI 10.4274/meandros.galenos.2021.65002.</mixed-citation><mixed-citation xml:lang="en">Ceri N.G., Gulle K., Arasli M., Akpolat M., Demirci B. Protective Effect of Vitamin B5 (Dexpanthenol) on Nephropathy in Streptozotocin Diabetic Rats// Meandros medical and dental journal, 2021. – Vol. 22. - P. 53-56. DOI 10.4274/meandros.galenos.2021.65002.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Kumrungsee T., Zhang P., Chartkul M., Yanaka N., Kato N. Potential Role of Vitamin B6 in Ameliorating the Severity of COVID-19 and Its Complications// Frontiers in Nutrition, 2020. - Vol. 7. – P.1-5. Article № 562061. https://doi.org/10.3389/fnut.2020.562051</mixed-citation><mixed-citation xml:lang="en">Kumrungsee T., Zhang P., Chartkul M., Yanaka N., Kato N. Potential Role of Vitamin B6 in Ameliorating the Severity of COVID-19 and Its Complications// Frontiers in Nutrition, 2020. - Vol. 7. – P.1-5. Article № 562061. https://doi.org/10.3389/fnut.2020.562051</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Mahmoodpoor A., Shadvar K., Sanaie S., Hadipoor M.R., Pourmoghaddam M.A., Saghaleini S.H. Effect of Vitamin C on mortality of critically ill patients with severe pneumonia in intensive care unit: a preliminary study // BMC Infectious Diseases, 2021. – Vol.21, 616. – P. 1-7. DOI: https://doi.org/10.1186/s12879-021-06288-0.</mixed-citation><mixed-citation xml:lang="en">Mahmoodpoor A., Shadvar K., Sanaie S., Hadipoor M.R., Pourmoghaddam M.A., Saghaleini S.H. Effect of Vitamin C on mortality of critically ill patients with severe pneumonia in intensive care unit: a preliminary study // BMC Infectious Diseases, 2021. – Vol.21, 616. – P. 1-7. DOI: https://doi.org/10.1186/s12879-021-06288-0.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Cruz P.L., Moraes-Silva I.C., Ribeiro A.A., Machi J.F., de Melo M.D.T., dos Santos F., da Silva M.B., Strunz C.M.C., Caldini E.G., Irigoyen M.C. Nicotinamide attenuates streptozotocin-induced diabetes complications and increases survival rate in rats: role of autonomic nervous system// BMC Endocrine Disorders, 2021. – Vol.21. – P. 1-10. Article №133. DOI: 10.1186/s12902-021-00795-6.</mixed-citation><mixed-citation xml:lang="en">Cruz P.L., Moraes-Silva I.C., Ribeiro A.A., Machi J.F., de Melo M.D.T., dos Santos F., da Silva M.B., Strunz C.M.C., Caldini E.G., Irigoyen M.C. Nicotinamide attenuates streptozotocin-induced diabetes complications and increases survival rate in rats: role of autonomic nervous system// BMC Endocrine Disorders, 2021. – Vol.21. – P. 1-10. Article №133. DOI: 10.1186/s12902-021-00795-6.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Fricker R.A., Green E.L., Jenkins S.I., Griffin S.M. The Influence of Nicotinamide on Health and Disease in the Central Nervous System. //International Journal of Tryptophan Research, 2018. – Vol. 11. – P. 1-11. DOI: https://doi.org/10.1177/1178646918776658.</mixed-citation><mixed-citation xml:lang="en">Fricker R.A., Green E.L., Jenkins S.I., Griffin S.M. The Influence of Nicotinamide on Health and Disease in the Central Nervous System. International Journal of Tryptophan Research, 2018. – Vol. 11. – P. 1-11. DOI: https://doi.org/10.1177/1178646918776658.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Абатуров А.Е., Волосовец А.П., Борисова Т.П. Медикаментозное управление окислительно восстановительным состоянием ор-ганизма при заболеваниях органов дыхания (часть 6) //Здоровье ребенка. Теоретическая медицина, 2018. – Т.13. - №8. - С. 783-796. DOI: 10.22141/2224-0551.13.8.2018.154160.</mixed-citation><mixed-citation xml:lang="en">Abaturov A.E., Volosovec A.P., Borisova T.P. Medikamentoznoe upravlenie okislitel'novosstanovitel'nym sostojaniem or-ganizma pri zabolevanijah organov dyhanija (chast' 6) //Zdorov'e rebenka. Teoreticheskaja medicina, 2018. – T.13. - №8. - S. 783-796. DOI: 10.22141/2224-0551.13.8.2018.154160. (in Russian).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
